Windows only: HoeKey is a tiny portable application that helps you create user-defined hot key combinations that control a wide variety of Windows functions.
HoeKey uses an astoundingly low amount of system resourcesâ€”on my system it used a mere 252k of memory. By comparison, the next most intensive non-system process was Notepad, consuming 1,298k of memory. Users can script a variety of macros going well beyond basic application launching. HoeKey has commands for emulating keystrokes, running applications, moving and manipulating windows, adjusting speaker volume and media playback, and a host of other things you might not want to do manually.
The application is completely portable and, because it doesn’t modify the system at all, you could safely use it for custom keyboard shortcuts  on a work computer. Use HoeKey with some of the free ways we’ve suggested for syncing your files , and you’ll have the convenience of the same keyboard shortcuts at both your home and office terminals. HoeKey is a free download for Windows systems only.
(Fonte: Lifehacker )